Regulus Therapeutics Inc. (RGLS) stock surged in the after-hours trading session; here’s why


In the aftermarket trading session, Regulus Therapeutics Inc. (RGLS) stock was up 5.44%, trading at $ 1.04 on the last check, while RGLS stock was down -4.24 in the normal trading session % fell. The RGLS share volume traded 0.4 million shares, which was below the average 3-month volume of 2.70 million shares over the past 3 months. So far last year, RGLS stock was up 31.51%, but last week, RGLS stock was down -0.79%.

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Here's what you need to know about Regulus Therapeutics:

Regulus Therapeutics Inc. is a clinical-stage biopharmaceutical organization specifically focused on the treatment of infections caused by mRNAs. The RGLS share is focused on discovering and enhancing the development of drugs against microRNAs for the treatment of a variety of infections in the United States. The two lead candidates include RG-012, an enemy of miR that is focused on miR-21 and is in Phase II clinical treatment for Alport's disease, a dangerous kidney disease. and RGLS4326, an enemy of miR focused on miR-17 and in Phase Ib, clinical preparatory to treatment of an autosomal predominant polycystic kidney infection. The organization is also sponsoring a pipeline of preclinical drugs containing RGLS5579 to help contain miR-10b, the hepatitis B infection program, and the alcohol-free steatohepatitis program. Regulus Therapeutics Inc. was founded in 2007 and is based in San Diego, California.

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The company's ADPKD program has made some progress and updates

Regulus Therapeutics Inc (NASDAQ: RGLS) announced an incremental update to the ADPKD program, which is an autosomal dominant polycystic kidney disease. This update was prepared using the outcome of the primary cohort of patients from the ongoing preliminary Phase 1b assessment of RGLS4326 in autosomal dominant polycystic kidney disease (ADPKD). ADPKD is a genetic disorder that is described by the development of various cysts in the kidneys. In the primary cohort, nine patients were selected and received 1 mg / kg RGLS4326 subcutaneously every other week for four doses. The mean expansion of polycystins 1 and 2 (lower protein levels associated with ADPKD) towards the end of the study compared to baseline for each of the nine patients in the primary cohort was 58% (p = 0.0004) 38%, separately.

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For the most part, as noted, treatment with RGLS4326 was very lengthy with no real adverse events reported. All of the detailed unfavorable occasions were gentle and mostly temporary. The information was presented at the Oppenheim Rare and Orphan Disease Summit on May 21, 2021. Additional information from this first cohort will be presented on PKD Connect in June 2021, and a publication will be submitted to the American Society of Nephrology's annual convention in November. Information from the following cohort is expected in the second quarter of the last quarter.

https://thedailytradingnews.com/regulus-therapeutics-inc-rgls-stock-surged-in-the-after-hours-trading-session-heres-why/

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