Bruce Bentley

1. Haroon M Gallagher P FitzGerald O Diagnostic delay of more than 6 months contributes to poor radiographic and functional outcome in psoriatic arthritis. Ann Rheum Dis. 2015; 74 : 1045-1050 2. Ritchlin CT Colbert R.A Gladman DD Psoriatic arthritis. N Engl J Med. 2017; 376 : 2095-2096 3. Coates LC Kavanaugh A Mease PJ et al. Group for research and assessment of psoriasis and psoriatic arthritis 2015 treatment recommendations for psoriatic arthritis. Arthritis Rheumatol. 2016; 68 : 1060-1071 4. Gossec L Baraliakos X Kerschbaumer A et al. EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2019 update. Ann Rheum Dis. 2020; 79 : 700-712 5. Singh YES Guyatt G Ogdie A et al. Special article: 2018 American College of Rheumatology/National Psoriasis Foundation guideline for the treatment of psoriatic arthritis. Arthritis Rheumatol. 2019; 71 : 5-32 6. Smolen JS Schols M Brown J et al. Treating axial spondyloarthritis and peripheral spondyloarthritis

take away Responding to a decline in the London Stock Exchange's global market share of IPOs and other fundraising, a string of government-commissioned reports prompted proposals to reform the UK's listing rules and other legal requirements. The rules now make it more attractive to list SPACs in London, and companies with dual-class share structures will be allowed to list on the Premium Segment. The minimum free float requirement has also been lowered. Rules for secondary issuances are also being revisited so companies can raise new equity without cumbersome rights offerings made to all existing shareholders. Regulatory Reforms Aim To Attract More Listings to London Following a year in which activity in the London primary equity markets was depressed by the pandemic, global lockdowns and volatility, the London Stock Exchange (LSE) saw more IPOs completed in the first quarter of 2021 than in the whole of 2020. By December 2021 , the figure was around three times the

HEADLINES Leverage loan technology and computer-related issuance in Western and Southern Europe almost doubled from annual pre-pandemic levels to €19.9 billion by the end of 2021 Technology and computer-related high yield bond issuance in the region hit an all-time high of €7.3 billion by the end of 2021 Start-up debt issuance in Europe had already reached a record annual total before the end of Q3 20211 Europe's technology industry went from strength to strength in 2021, with M&A and lending activity in the space thriving as investors across multiple asset classes tapped into the tech sector's non-stop growth and resilience. The shift to home working due to COVID-19, as well as the rise in digital learning and online shopping and entertainment through both 2020 and 2021, drove earnings growth across the entire technology sector. Safe and secure technology was a must-have in every home, which ensured that tech firms were kept busy, lifting revenues and promptin

G armin's latest top-of-the-line Fenix ​​7 track-it-all adventure smartwatch introduces a number of new features, better GPS, longer battery life and improved tech – as well as a touchscreen to go with its buttons. Starting at £599 ($699.99/A$1,049), it can hit £1,000 or more if you pick the largest, most fancy version. But the new luxury device does give us a preview of what the firm's cheaper sports watches may feature later in the year. The Fenix ​​7 comes in a range of sizes, weights, materials and with an optional solar-charging system, all of which have full mapping. The new model looks like a refinement rather than a revolution away from previous Fenix ​​designs. The 7S is the smallest, sleekest version with a 42mm case and 1.2in screen, although it's still obviously a sports watch. The standard 7 and supersized 7X are larger, chunkier beasts but are still light and comfortable to wear. The watch has a charging port on the back and special quick-release straps but

Hackers with suspected links to China targeted News Corp 's third-party technology suppliers, according to a company filing. News Corp, which owns the New York Post and The Wall Street Journal parent Dow Jones, said it was the target of a hack that accessed emails and documents of journalists and other employees. The company in a securities filing on Friday said it “relies on third-party providers for certain technology and 'cloud-based' systems and services that support a variety of business operations,” and that one of these systems “was the target of persistent cyber attack activity.” The attack came as US officials over the past year have been increasingly warning of criminal and nation-state hackers breaking into the computer systems of organizations through sometimes opaque supply chains for software and other technologies. A News Corp spokesman on Friday declined to comment on its vendors or which data was stolen, citi

A 3D printed Facebook's new rebrand logo Meta is placed on laptop keyboard in this illustration taken on November 2, 2021. REUTERS/Dado Ruvic/Illustration/File Photo Register now for FREE unlimited access to Reuters.com register Feb 2 (Reuters) - Facebook owner Meta Platforms Inc (FB.O) shares plunged more than 20% late on Wednesday as the social media company missed on Wall Street earnings estimates and posted a weaker-than-expected forecast. Meta said it faced hits from Apple Inc's (AAPL.O) privacy changes to its operating system, which have made it harder for brands to target and measure their ads on Facebook and Instagram, and from macroeconomic issues like supply-chain disruptions. read more The tech giant said it expected slowing revenue growth in the coming quarter because it faced increased competition for users' time and a shift of engagement toward such features as its short video offering reels, which generate less revenue. Register now for FREE unlimited access